Tohru Yamada Selected Research

cupredoxin

1/2014	A nanotechnological, molecular-modeling, and immunological approach to study the interaction of the anti-tumorigenic peptide p28 with the p53 family of proteins.
9/2011	A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt.
1/2009	Noncationic peptides obtained from azurin preferentially enter cancer cells.
2/2007	Cupredoxin-cancer interrelationship: azurin binding with EphB2, interference in EphB2 tyrosine phosphorylation, and inhibition of cancer growth.
10/2005	Internalization of bacterial redox protein azurin in mammalian cells: entry domain and specificity.
3/2004	Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer.

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Tohru Yamada Research Topics

Disease

22	Neoplasms (Cancer) 01/2022 - 10/2002
9	Breast Neoplasms (Breast Cancer) 02/2022 - 03/2004
5	Melanoma (Melanoma, Malignant) 01/2014 - 10/2002
2	Brain Neoplasms (Brain Tumor) 01/2016 - 08/2006
2	Carcinogenesis 04/2013 - 03/2011
1	Central Nervous System Neoplasms 01/2016
1	Body Weight (Weight, Body) 04/2013
1	Parkinson Disease (Parkinson's Disease) 12/2011
1	Parkinsonian Disorders (Parkinsonism) 12/2011
1	Endometriosis 03/2011
1	Leiomyoma (Uterine Fibroids) 03/2011
1	Priapism 03/2007
1	Wounds and Injuries (Trauma) 03/2007
1	Prostatic Neoplasms (Prostate Cancer) 02/2007
1	Acquired Immunodeficiency Syndrome (AIDS) 08/2006
1	Meningitis 08/2006
1	Malaria 08/2006
1	Infections 08/2006
1	Falciparum Malaria (Plasmodium falciparum Malaria) 08/2006
1	Parasitemia 08/2006
1	Glioblastoma (Glioblastoma Multiforme) 08/2006
1	Coinfection 08/2006
1	Retinoblastoma (Glioblastoma, Retinal) 04/2004

Drug/Important Bio-Agent (IBA)

12	AzurinIBA 01/2014 - 10/2002
10	Proteins (Proteins, Gene)FDA Link 01/2016 - 10/2002
6	Cell-Penetrating PeptidesIBA 01/2022 - 01/2009
6	cupredoxinIBA 01/2014 - 03/2004
5	DNA (Deoxyribonucleic Acid)IBA 02/2022 - 09/2013
5	Peptides (Polypeptides)IBA 01/2016 - 08/2006
4	Amino Acids FDA Link 09/2011 - 08/2006
2	Tumor Suppressor Protein p53IBA 01/2014 - 10/2002
2	CopperIBA 01/2009 - 03/2004
2	rusticyaninIBA 10/2005 - 09/2004
1	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2022
1	Dacarbazine (DIC)FDA LinkGeneric 01/2016
1	Antimitotic AgentsIBA 01/2016
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2016
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2016
1	azurin (50-77)IBA 01/2016
1	Docetaxel (Taxotere)FDA Link 01/2016
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2015
1	Protein Isoforms (Isoforms)IBA 01/2014
1	Bexarotene (LGD1069)FDA Link 04/2013
1	Antineoplastic Agents (Antineoplastics)IBA 04/2013
1	Biomarkers (Surrogate Marker)IBA 04/2013
1	AntibodiesIBA 04/2013
1	Estrogen ReceptorsIBA 04/2013
1	RetinoidsIBA 04/2013
1	Pramipexole (Mirapex)FDA LinkGeneric 12/2011
1	Dopamine Agonists (Dopamine Agonist)IBA 12/2011
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 09/2011
1	SteroidsIBA 03/2011
1	telapristone acetateIBA 03/2011
1	CarcinogensIBA 03/2011
1	Hormones (Hormone)IBA 03/2011
1	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 03/2011
1	Progesterone FDA LinkGeneric 03/2011
1	Progesterone Receptors (Progesterone Receptor)IBA 03/2011
1	Ligases (Synthetase)IBA 01/2011
1	UbiquitinIBA 01/2011
1	CaveolinsIBA 10/2009
1	Peptide FragmentsIBA 10/2009
1	GlycosaminoglycansIBA 01/2009
1	Cytostatic AgentsIBA 01/2009
1	EphrinsIBA 02/2007
1	Tyrosine (L-Tyrosine)FDA Link 02/2007
1	Merozoite Surface Protein 1 (MSA1)IBA 08/2006
1	Cysteine (L-Cysteine)FDA Link 08/2006
1	Antimalarials (Antimalarial Agents)IBA 08/2006
1	EpitopesIBA 08/2006
1	Alanine (L-Alanine)FDA Link 08/2006
1	Cytochromes c (Cytochrome c)IBA 12/2005
1	Green Fluorescent ProteinsIBA 10/2005
1	Glutathione Transferase (Glutathione S-Transferase)IBA 10/2005
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2004
1	Caspase 8 (Caspase-8)IBA 09/2004
1	Bacterial Proteins (Bacterial Protein)IBA 06/2004
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 04/2004

Therapy/Procedure

3	Therapeutics 01/2014 - 06/2004
1	Computer-Assisted Surgery (Image Guided Surgery) 02/2022
1	Segmental Mastectomy (Lumpectomy) 01/2022
1	Catheters 03/2007